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INTRODUCTION
Bernard M. Wagner Department of Pathology, School of Medicine, University of Washington, Seattle, Wash.
Following the elaboration of the concept "collagen diseases," an enormous investigative effort probing this idea has developed. Almost all branches of the biological sciences are currently involved in research related to collagen or connective tissue. From the physical chemist to the clinician, from the electron microscope to the whirlpool bath, the vast diversity of talents concerned with the common denominator, connective tissue, is apparent in the scientific literature. As the research expands and builds in complexity, it is vital that all lines of communication remain open and functional.
One of the purposes of this monograph is to bring together contributions from outstanding representatives in the field of connective tissue research. The contributors cover all phases, from a consideration of fiber formation and wound healing to reviewing immunological phenomena in connective tissue disease. This is an area under intensive investigation, and many aspects are in dispute. The use of new tools is briefly presented, and there is a review of host factors. This monograph contains stimulating material deliberately planned to evoke spirited discussion and to stimulate renewed effort in the field.