Acta Biologica Tomus XXXIII. Fasciculi 1-4. [antikvár]

Acta Biol. Szeged. 33. pp. 3 —5 (1987) ON THE 60TH BIRTHDAY OF PROFESSOR DR. OTTÓ FEHÉR Ottó Fehér was born in Debrecen in 1927. He was educated in the Protestant College of Debrecen and took his medical diploma at the University Medical School. As a student he joined the Department of Physiology headed at that time by Professor István Went and became involved in the experimental work about regulation of heart and blood circulation. After having finished his studies in 1951, he began postgraduate course in physiology of the nervous system. In examining the problems of synaptic transmission in the symphatetic ganglia he proved that in the postsynaptic membrane of ganglion cells there are two sorts of acetylcholine receptors: a nicotinic type and a muscarinic type, differing in their physiological role and pharmacological responsiveness. This discovery has been confirmed in the international literature repeatedly and gave starting point of the modern theory of neural membrane receptors. It was subsequently proved that denervation and decentralization supersensitivity can be ascribed to redistribution of the two kinds of receptors in the post-synaptic membrane. In these studies he was aided by his first co-worker and friend Emil Bokri and students being active in scientific student society: sándor Damjanovich, Péter Halász, Ferenc Mechler, Elemér Lábos,