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PREFACEThe incredible extent to which man has debased, and continues to debase, the environment in both a chemical and physical sense is becoming increasingly apparent. This has dictated an unparalleled need both to determine the parameters of this abuse as well as to marshall a mulli-discipHned approach for its curtailment.Chromatography of Environmental Hazards is a series of three volumes devoted to the elaboration of chromatographic procedures (primarily paper, thin-layer, and gas-liquid) that relate to the analyses of a broad spectrum of synthetic and naturally occurring toxicants that are of critical significance to the health of man and animals alike. The first volume centers on toxicants of carcinogenic, mutagenic, and teratogenic significance. The second and third volumes will focus on air, water, industrial pollutants, metals, pesticide residues, and drugs (narcotics, psychotropic agents, hallucinogens and miscellaneous drugs), respectively.The main objective of this series is to provide the analytical chemist with both a practical text as well as a literature reference source of selected descriptive chromatographic procedures that stress the separation, detection, and determination of toxicants from environmental sources, biologic media, and mammahan and plant sources. However, relevant information has been included, where available, regarding the synthesis or occurrence, areas of utility, sahent biological and physical properties, chemical stabihty, and degradation and metabohc fate of the toxicants that is of importance to investigators in diverse disciphnes that include biochemistry, biology, genetics, molecular biology, toxicology and public health, all equally concerned, as well as others, with amehorating or eliminating the effects of these environmental hazards.I acknowledge with deep gratitude the efíbrts of Mrs. Peggy Sauls in the assembly, typing and proofing of the manuscript.L. FISHBEIN