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PREFACE TO THE FOURTH EDITION
As long as tranquilizers have existed, critical voices have warned against
prescribing psychotropic drugs indiscriminately. There is certainly more
than a grain of truth in this. On the other hand, the problem for the
medical practitioner is that there is an ever greater and more complex
range of these now indispensable agents and their action is increasingly
specific and differentiated.
In the preface to an earlier edition of the Compendium of Psychopharmaco-
therapy Professor Kielholz wrote: 'In its first edition, this compendium
sought to illuminate the problems confronting the non-psychiatrist and
help him familiarize himself with the great number of drugs at his dis-
posal and select the right one for the individual case.' I have nothing
new to add to these words, but would merely like to stress them. How-
ever, the expansion, transformation and increased sophistication of the
subject over the past decade have revealed the urgency of adapting this
monograph for the revised edition planned by Editiones
.
In our field, specific clinical pharmacotherapy is unthinkable without
neurophysiology and neuropharmacology. Professor Willy Haefely,
M.D., of Basle, has kindly accepted the task of clearly and concisely
formulating the most recent findings from his field of research in a
special chapter which is the actual crystallization point of the revised
Compendium. I am indebted to François Wider of Sarnen - author of the
standard work Psychoactive Drugs - for the updated drug table. Wolfgang
Kolditz, M.D., of Basle, took in hand the task of editing and, together
with myself, defined the priorities for a modern approach. We have
omitted historical passages, digressions on psychostimulants, outdated
biochemical (in part, still theoretical) expositions and speculative polem-
ics on the misuse of psychotropics to make as much space as possible
available for practical problems: alcohol and its interaction with other
medication, the danger of suicide, selective use or avoidance of specific
side effects, behaviour in traffic. I am also indebted to my colleague
W. Kolditz for recasting the bibliography in a more convenient form at