Haemate P [antikvár]

Introduction Haemophilia A is the most com-mon hereditary plasma coagulation disorder and is characterized by absence of or réduction in Factor VIII activity (F VIII: C). Diagnosis is based upon the clinical picture, the family history and détermination of Factor VIII activity. Haemophilia is characterized by serious spontaneous, posttrau-matic ahd postoperative bleed-ings. Bloeding into joints and muscles, which occurs-chicfly in children and adolescents, may lead to severe handicap and invalidity.pitracranial hacmor-rhages are a commori cause of death. The haemorrhages and their conséquences can be prevented to a considérable extent by timely substitution of the missing clotting factor in sufficiënt quantifies (21,56). Treatmentwith Factor \f[| cor!g| centrâtes is not, however, without problems, as there is a risk of concomitant side effects, not least the risk posed by transmission of virus infections. Inteifc sive purification combined with the special pasteurization stage (heating in aqueous solution for 10 hours at 60 °C in the presence of suitable stabilizers) ensures that Haemate P provides a high degree of safety from virus infections. It is a high purity concentrate which entails a minimal protein loading for the patient.