Metabolism of the Hypoxic and Ischaemic Heart I-II. [antikvár]

Foreword Clinical, experimental, and epidemiological studies on ischaemic heart disease, hypertension, and cardiomyopathies have shown the need for more intensive investigation of the function of the myocardium and the morphological changes that take place in it. During the course of 1971, the International Society of Cardiology and the World Health Organization sponsored three meetings to review the present state of knowledge in this field and to examine current research projects and future trends. The present volume contains the Proceedings of the second of these meetings, which was held in Geneva from 14 to 17 June 1971. It was preceded by a meeting in Pisa, which lasted from 12 to 14 June and was concerned with myocardial blood flow in man. The third meeting, to discuss neural and psychological mechanisms in cardiovascular disease, took place in Stresa from 19 to 21 July. The Geneva meeting was organized jointly by the Council on Clinical Science of the International Society of Cardiology and the World Health Organization, with the participation of the Centre of Cardiology of the University of Geneva (Director: Professor P. W. Duchosal). All three organizations have been co-operating in a number of activities during the past ten years. Professor J. Lequime, President of the International Society of Cardiology, and Dr. P. Dorolle, Deputy Director-General of the World Health Organization, in their opening addresses, both emphasized the fruitfulness of such close contact in promoting research, accelerating the application of new knowledge, and furthering postgraduate studies in cardiology. In organizing the Symposium care was taken to secure a wide multi-disciplinary representation and emphasis was placed on the informal discussions that followed the presentation of the introductory papers. In addition to reviewing the metabolic changes that occur in the heart during chronic hypoxia and ischaemia, the participants tried to relate these changes to the chemical composition of the heart cell, to the electrical activity of the heart, and to structural and mechanical changes in the myocardium. Hypoxia