Molecular Cell Biology [antikvár]

Preface Biology today is scarcely recognizable as the subject that biologists knew and taught 10 years ago. A decade ago, gene structure and function in the simple cells of bacteria were known in considerable detail. But now we also know that a different set of molecular rules governs gene organization and expression in all eukaryotic cells, including those of humans. We are learning about the genes and regulatory proteins that control not only single metabolic steps but complicated developmental events such as the formation of a limb, a wing, or an eye. In addition to these advances in understanding the genetic machinery and its regulation, great progress has been made in the study of the structure and function of cell organelles and of specialized cell proteins. To comprehend fully what has been learned requires a reformulation of a body of related information formerly classified under the separate headings of genetics, biochemistry, and cell biology. Molecular Cell Biology aims to present the essential elements of this new biology. Traditionally, the sciences of genetics, biochemistry, and cell biology—the three areas in which the greatest progress has been made in the last 25 to 30 years—used different experimental approaches and often different experimental material. Classical geneticists sought mutations in specific genes to begin identifying the gene products and characterizing their physiological functions. Biochemists tried to understand the actions of proteins,